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. 2016 Aug 26;10(Suppl 3):62. doi: 10.1186/s12918-016-0306-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Coefficient matrix (H). The coefficient matrix (H), 3 × 358 in size, is used for assigning samples to clusters. The columns of the matrix represent patients and rows represent metagenes. We generated 3 metagenes that are used to cluster patients into 3 groups. The number of metagenes (rank of clustering) is determined by running the algorithm iteratively over a range of biologically reasonable parameters as explained in methods section