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. 2016 Aug 31;17(Suppl 5):530. doi: 10.1186/s12864-016-2828-6

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The visualization interface of I n t e G O2 to explore gene functional similarities based on GO. The network is shown in panel (c), in which a node represents a gene, and an edge indicates that the similarity score between the two corresponding genes is larger than an edge similarity threshold, which can be changed in panel (a). Edge similarity scores distribution shown in panel (b) helps users to choose an appropriate threshold. The gene information panel (d) and (e) show the recently chosen genes and current gene respectively. Panel f shows the neighbors of the recently chosen genes. The node operation panel (g) allows users to flag, lock or unlock a gene. The selected subnetwork is shown in (h)