Table 1:
Four-year nonpersistence and restart rates among 14 349 new medication users, using algorithms with vs without medication stockpile in the definition for the allowable gap
| Definition of allowable gap | Nonpersistence % (95% CI) | Restartsa % (95% CI) |
|---|---|---|
| LDS + medication stockpile + grace period of | ||
| 30 days | 66 (65-67) | 74 (73-75) |
| 75 days | 52 (51-52) | 57 (56-59) |
| 100 days | 46 (45-47) | 48 (47-49) |
| 180 days | 36 (35-37) | 29 (27-30) |
| 300 days | 28 (28-29) | 9 (8-10) |
| LDS + grace period of | ||
| 30 days | 81 (80-82) | 81 (81-82) |
| 75 days | 59 (58-60) | 64 (62-65) |
| 100 days | 51 (50-51) | 53 (52-54) |
| 180 days | 37 (36-38) | 30 (29-31) |
| 300 days | 29 (28-30) | 9 (8-9) |
aPercentage of patients who were nonpersistent and had a dispensing of the index therapy within 1 year of the estimated date of nonpersistence.
LDS = last days’ supply dispensed.