Rewiring scores of the ribosomal regulon for RAP1-TBF1 and IFH1-CBF1 switches across branches. The rewiring scores are shown on the y-axis, and the selected branches are shown on x-axis. (A) RAP1 in lineage and TBF1 in ancestral species: This plot compares the RS distribution of the background (all genes, in white) and that of ribosomal genes (in gray) for the potential that RAP1 regulates its member genes in species diverging from a given branch b, and TBF1 regulates the ancestral species. (B) TBF1 in lineage and RAP1 in ancestral species: This plot compares the rewiring score distribution of the background (in white) and that of ribosomal genes (in gray) for the potential that TBF1 regulates its member genes in species diverging from a given branch b, and RAP1 regulates the ancestral species. (C) and (D) are analogous to (A) and (B), respectively, for the IFH1-CBF1 switch in RP genes.