Table 1. Optimization of the Pd/Cu-Catalyzed Enantioselective Hydroarylation of Styrenea.
Yields determined by GC analysis of the crude reaction mixture using tetradecane as an internal standard; enantioselectivity of the purified product was determined by chiral HPLC; ND = not determined.
Cu(OAc)2 used as the Cu source.
CuOAc used as the Cu source.