. 2016 Aug 8;18(16):4128–4131. doi: 10.1021/acs.orglett.6b02082

Table 1. Initial N-Arylation Experiments^a.

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Reaction conditions: phenylalanine tert-butyl ester free base (5a, 1.2 equiv), electrophile (1 equiv), P1 (1 mol %), base (1.2 equiv).

Isolated yields.

Enantiomeric excess (ee) was determined by HPLC analysis using chiral stationary phases.

Table 1. Initial N-Arylation Experimentsa.