Fig. 3.

UA and UCA encapsulated within PMPC₂₅-PDPA₆₅ polymersomes (dotted lines) and tubes (dashed lines), elicit dose dependent increases in fibroblast ATP levels similar to when dissolved in 0.1% DMSO (solid lines). Control (grey) and matched parkin-mutant fibroblasts (black) were incubated with formulations of UA for (a) 24 and (b) 48 h, as well as UCA formulations for (c) 24 and (d) 48 h (error bars = SD, n = 3).