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. 2016 Aug 29;9:261–272. doi: 10.2147/DMSO.S109599

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© 2016 Suman et al. This work is published and licensed by Dove Medical Press Limited

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Histopathological section of liver.

Notes: (A) Photomicrograph of liver sections of NC rats shows normal architecture of liver. (B) In contrast, the liver of HF-DC group rat shows fatty liver, moderate fatty degeneration, ballooning of cell, inflammatory infiltration more, and congestion of blood vessels in the central vein. (C) In the MET group rats, liver shows less fatty degeneration, inflammatory infiltration, congestion of blood vessels, fibrosis, edema, and necrosis. (D) In the VIL group rats, liver shows less fatty degeneration, inflammatory infiltration, edema, and necrosis. (E) In the MNG group rats, liver shows less inflammatory infiltration, edema, and normal structure of central vein, peripheral vein, and no congestion of sinosoides. Magnification 40×.

Abbreviations: NC, normal control; HF-DC, high-fat diabetic control; MET, metformin; VIL, vildagliptin; MNG, mangiferin.