Table 3.
Immunohistochemical detection of brachyury in biopsies obtained from metastatic lesions of TNBC patients.
| Nuclear brachyury | Cytoplasmic brachyury | Total brachyury | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pt | Site | Ki67 | p53 | Pos (%) | SI | Index | Pos (%) | SI | Index | Pos (%) | SI | Index |
| 78 | LN | 30 | NEG | 100 | +++ | 300 | 100 | + | 100 | 100 | +++ | 300 |
| 79 | LN | 90 | NEG | 90 | +++ | 270 | 50 | + | 50 | 100 | +++ | 300 |
| 80 | LN | 65 | POS | 80 | +++ | 240 | 0 | - | 0 | 80 | +++ | 240 |
| 81 | LN | 50 | NEG | 70 | +++ | 210 | 50 | + | 50 | 80 | +++ | 240 |
| 82 | LN | 70 | NEG | 80 | +++ | 240 | 0 | - | 0 | 80 | +++ | 240 |
| 84 | Dist | 90 | NEG | 80 | +++ | 240 | 20 | + | 20 | 80 | +++ | 240 |
| 86 | Dist | 60 | NEG | 60 | ++ | 120 | 70 | ++ | 140 | 80 | ++ | 160 |
| 83 | Dist | 50 | NEG | 60 | +++ | 180 | 40 | ++ | 80 | 70 | +++ | 210 |
| 87 | Dist | 10 | POS | 60 | +++ | 180 | 20 | + | 20 | 60 | +++ | 180 |
| 85 | Dist | 80 | NEG | 30 | ++ | 60 | 20 | + | 20 | 40 | ++ | 80 |
SI: Staining Intensity; NEG: negative; POS: positive. LN: lymph node; Dist: distant metastasis