. Author manuscript; available in PMC: 2017 Oct 1.

Published in final edited form as: Endocr Relat Cancer. 2016 Oct;23(10):783–796. doi: 10.1530/ERC-16-0037

Table 4.

Multivariate Cox Proportional-Hazards Regression analysis of the predictive value of clinical-pathological variables and brachyury expression on relapse-free survival of TNBC patients.

		Recurrence
Variable	n	Yes	No	HR (CI)	p value
*Stage of disease*
I	21	2 (10%)	19 (90%)
II	24	4 (17%)	20 (83%)
III	13	4 (31%)	9 (69%)	1.83 (0.60 – 5.57)	0.285
*p53 expression*
Negative	26	4 (15%)	22 (85%)
Positive	32	6 (19%)	26 (81%)	1.34 (0.30 – 5.91)	0.699
**Brachyury expression^***
Negative (<240)	41	5 (12%)	36 (88%)
Positive (≥240)	17	5 (29%)	12 (71%)	3.92 (1.02 – 15.1)	*0.047*

Categorized according to an arbitrary cutoff calculated as the 75^th percentile of brachyury reactivity index for total brachyury staining in the overall population (n=87).