Table 4.

C-statistic of sudden cardiac death with echocardiographic variables added to the Framingham risk score

	ARIC C-statistic (95% CI)	CHS C-statistic (95% CI)
Framingham risk score	0.608 (0.526–0.690)	0.669 (0.638–0.700)
FRS + Univariate: (each variable added to the score separately)
Mitral annular calcification	0.648 (0.567–0.729)	0.677 (0.633–0.721)
Reduced LV ejection fraction	0.659 (0.573–0.744)	0.719 (0.688–0.750)
Aortic sclerosis	0.620 (0.535–0.705)	0.671 (0.628–0.714)
Left atrium diameter, continuous	0.608 (0.522–0.694)	0.669 (0.637–0.702)
Left atrium diameter, tertiles	0.619 (0.537–0.702)	0.669 (0.637–0.701)
Aortic root diameter, continuous	0.682 (0.609–0.756)	0.666 (0.635–0.697)
Aortic root diameter, tertiles	0.637 (0.564–0.710)	0.666 (0.635–0.697)
LV mass index, continuous	0.648 (0.542–0.755)	0.687 (0.645–0.728)
LV mass index, tertiles	0.623 (0.538–0.707)	0.670 (0.628–0.712)
Mitral E/A, continuous	0.629 (0.542–0.715)	0.666 (0.634–0.698)
Mitral E/A, categories	0.633 (0.553–0.713)	0.671 (0.639–0.703)
Mitral Peak E, continuous	0.644 (0.552–0.735)	0.668 (0.635–0.700)
FRS + Multivariate: (all variables added to the score)	0.764 (0.657–0.870)	0.741 (0.687–0.749)