Table 3.
IC50 values of the compounds with different substituent on the thiophene 4- and 5-position.
| Compound | R2 | R3 | IC50 (µM) | |
|---|---|---|---|---|
 |
4a |  |
 |
>50 |
| 4b |  |
 |
>50 | |
| 4c |  |
 |
>50 |
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