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. 2016 Aug 29;9:5383–5388. doi: 10.2147/OTT.S106906

Figure 3.

Figure 3

Pitavastatin induced apoptosis of liver cancer cells dependent of caspase.

Notes: (A) Alteration of apoptosis-related protein expression after pitavastatin treatment for 48 hours. (B) Quantitative analysis of protein expression with pitavastatin treatment. Huh-7 cells without treatment were used as a Ctrl. The relative expression was presented as pitavastatin-treated cells/DMSO-treated cells. (C) Reversal effect of caspase inhibitor Z-VAD-FMK on pitavastatin prohibited cell growth. Huh-7 cells without treatment were used as a Ctrl. The relative expression was presented as pitavastatin- or Z-VAD-FMK-treated cells/DMSO-treated cells. *P<0.05, **P<0.001, and ***P<0.01.

Abbreviations: Ctrl, control; DMSO, dimethyl sulfoxide.