Figure 1.
Effect of DcR3-specific siRNA on cell growth in glioma cell lines.
Notes: U251MG, LN-308, and U87MG cells (2.5×103 cells per well in 96-well plate) were cultured for 24 hours and then transfected with negative siRNA, scrambled siRNA, and DcR3-specific siRNA and incubated for another 96 hours. Cell viability (U251MG (A), LN-308 (B), and U87MG (C)) and cell proliferation (U251MG (D), LN-308 (E), and U87MG (F)) were assessed by MTS tetrazolium assay and fluorimetric resorufin viability assay, respectively. *P<0.05, **P<0.01, and ***P<0.001 compared to negative siRNA controls and scrambled siRNAs at the same time point.
Abbreviation: siRNA, small interfering RNA.