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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Food Chem Toxicol. 2016 Jul 16;95:188–195. doi: 10.1016/j.fct.2016.07.017

Table 3.

Effects of single or sequential AFB1 and FB1 treatments on liver GST-P+ foci development.

Groups N No. of foci
(No./cm2)		 Foci area ratio
(mm2)/(cm2)×1000		 Mean foci area
(mm 2)×1000		 Detection rate
of foci
Negative control 10 0.2±0.3* 1±3* 1±2* 1/10
AFB1 13 1.6±0.6* 7±6* 5±5* 13/13
FB1 13 0.9±1.0* 6±10* 4±4* 9/13
AFB1 + FB1 13 11.6±4.7 350±210 30±1 13/13
Positive control 13 50.4±10.0 5600±1200 105±20 13/13

The positive control group (DEN/2-AAF initiation promotion model) was not included in the statistical analysis of differences among the AFB1-only, FB1-only, and AFB1+FB1 treatment groups.

*

p < 0.05, compared to the AFB1+FB1 group.