Table 4.
Associations between prevalence of diabetes and quartiles of serum concentrations of PCBs grouped by number of ortho-substituted chlorines.
| Variables | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | Wald χ2 p-value |
|---|---|---|---|---|---|
| Non-/mono-ortho PCBs | |||||
| N (diabetics) | 153 (9) | 154 (13) | 149 (31) | 145 (58) | |
| Model 1 | |||||
| OR (95% CI) | 1.0 (ref) | 1.03 (0.41, 2.60) | 2.78 (1.17, 6.59) | 5.66 (2.23, 14.34) | |
| p-Value | — | 0.95 | 0.02 | 0.0003 | < 0.0001 |
| Model 2 | |||||
| OR (95% CI) | 1.0 (ref) | 1.03 (0.37, 2.86) | 2.37 (0.84, 6.73) | 4.55 (1.48, 13.95) | |
| p-Value | — | 0.95 | 0.10 | 0.0081 | 0.0036 |
| Di-ortho PCBs | |||||
| Model 1 | |||||
| N (diabetics) | 154 (16) | 151 (9) | 150 (34) | 146 (52) | |
| OR (95% CI) | 1.0 (ref) | 0.36 (0.14, 0.88) | 1.40 (0.63, 3.11) | 2.46 (1.02, 5.95) | |
| p-Value | — | 0.026 | 0.42 | 0.046 | 0.0004 |
| Model 2 | |||||
| OR (95% CI) | 1.0 (ref) | 0.27 (0.10, 0.74) | 0.79 (0.30, 2.11) | 1.26 (0.43, 3.69) | |
| p-Value | — | 0.011 | 0.64 | 0.67 | 0.0059 |
| Tri-/tetra-ortho PCBs | |||||
| Model 1 | |||||
| N (diabetics) | 152 (11) | 152 (14) | 150 (35) | 147 (51) | |
| OR (95% CI) | 1.0 (ref) | 0.97 (0.40, 2.32) | 2.62 (1.11, 6.17) | 4.18 (1.63, 10.70) | |
| p-Value | — | 0.94 | 0.028 | 0.0029 | 0.0015 |
| Model 2 | |||||
| OR (95% CI) | 1.0 (ref) | 0.88 (0.34, 2/30) | 1.86 (0.68, 5.06) | 2.90 (0.99, 8.51) | |
| p-Value | — | 0.80 | 0.23 | 0.053 | 0.042 |
|
Note: The number (N) of subjects in each quartile is given and the number of subjects with diabetes is given in the parentheses. Model 1–results are adjusted for age, gender, BMI, and serum concentrations of total lipids, but not total pesticides. Model 2–results are adjusted for total pesticides as well as age, gender, BMI, serum concentrations of total lipids. Wald χ2 test evaluates the significance of the differences in proportions across all quartiles. | |||||