Table 2.
Base Case | Low Case | High Case | Sources | |
---|---|---|---|---|
| ||||
Costs of misoprostol intervention (US$ 2013) | ||||
Matrone training cost | $1.68 | $1.35 | $2.10 | Base: Main study; Low: −25% of base case; High: +25% of base case |
Commodity cost | $0.42 | $0.34 | $0.53 | Same |
Cost of commodity wastage | $0.02 | $0.02 | $0.03 | Same |
Cost of cold chain | $0.00 | $0.00 | $0.00 | Base: Side study**; Low: −25% of base case; High: +25% of base case |
Distribution/use cost | $0.09 | $0.07 | $0.11 | Same |
Costs of oxytocin intervention (US$ 2013) | ||||
Matrone training cost | $1.86 | $1.49 | $2.33 | Same |
Commodity cost | $1.44 | $1.15 | $1.80 | Same |
Cost of commodity wastage | $0.17 | $0.14 | $0.22 | Same |
Cost of cold chain | $0.84 | $0.67 | $1.05 | Same |
Distribution/use cost | $0.06 | $0.05 | $0.08 | Same |
Cost of SOC (US$ 2013) | ||||
Minimal inputs | $1.00 | $0.80 | $1.25 | We assume a cost of $1 for SOC (matrones time, incidental medicines such as analgesics) |
Outcomes under misoprostol* | ||||
Proportion of delivering women referred due to PPH | 0.000 | 0.000 | 0.012 | Base: Main study; Low and High: 95% confidence interval |
Outcomes under oxytocin* | ||||
Proportion of delivering women referred due to PPH | 0.002 | 0.000 | 0.020 | Base: Main study; Low and High: 95% confidence interval |
Other rates | ||||
Proportion of delivering women with severe PPH | 0.032 | 0.025 | 0.040 | Base: Several studies***; Low: −25% of base case; High: +25% of base case |
Proportion of delivering women receiving misoprostol | 0.984 | 0.982 | 0.987 | Base: Main study; Low and High: 95% confidence interval |
Proportion of delivering women receiving oxytocin | 0.958 | 0.954 | 0.961 | Base: Main study; Low and High: 95% confidence interval |
The differences between the outcomes of the misoprostol and oxytocin interventions were not statistically significant.
Study of cold chain of ministry of health conducted by an independent consultant using unpublished government reports and data.
Carroli et al. 2008: Bateman et al. 2010; Derman et al. 2006; Govt. of India 2013; Mehrabadi et al. 2012; Mobeen et al. 2011; Oyelese and Anath 2010; and Prata et al. 2007.