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. Author manuscript; available in PMC: 2017 Sep 2.
Published in final edited form as: J Org Chem. 2016 Aug 10;81(17):8035–8042. doi: 10.1021/acs.joc.6b01421

Table 2.

Alkylation of Sulfonamides with Imidate 2.

graphic file with name nihms-809464-t0005.jpg
a

Yield for a modified procedure using 10 mol % BF3•OEt2 in toluene at room temperature with the imidate being added as a refluxing solution of sulfonamide with a syringe pump over 1 hour.

b

Starting sulfonamide 24 recovered unchanged.