Table 1.
Sequential DXA Spine and Hip Findings
| DXA Site & Parameter | Year (patient age, yrs) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Year Age (Yrs) | Normal BMD | Increased BMD Peak | ||||||||
| 1990* (17) | 1991* (18) | 2003 (30) | 2005 (32) | 2007 (34) | 2009 (36) | 2010 (37) | 2012 (39) | 2014 (41) | 2015 (42) | |
| L1 – L4 Spine | ||||||||||
| g/cm2 | 0.957 | 0.939 | 1.577 | 1.693 | 1.895 | 2.005 | 2.070 | 2.001 | 1.878 | 1.776 |
| BMC (g) | - | 31.9 | 69 | 74.9 | 85.3 | 91 | 94.1 | 90.9 | 84.9 | 80.4 |
| Area (cm2) | - | 33.97 | 43.8 | 44.2 | 45 | 45.4 | 45.5 | 45.4 | 45.2 | 45.3 |
| Z-score | - | - | +3.8 | +4.8 | +6.4 | +7.3 | +7.9 | +7.3 | +6.4 | +5.6 |
| Femoral Neck | ||||||||||
| g/cm2 | - | - | 0.762 | 0.732 | 0.798 | 0.815 | 0.844 | 0.820 | 0.864 | 0.813 |
| BMC (g) | - | - | 3.5 | 3.6 | 3.7 | 3.8 | 3.8 | 3.7 | 3.9 | 3.7 |
| Area (cm2) | - | - | 4.6 | 4.9 | 4.7 | 4.6 | 4.6 | 4.5 | 4.5 | 4.6 |
| Z-score | - | - | −1.4 | −1.7 | −1.1 | −0.9 | −0.7 | −0.8 | −0.4 | −0.8 |
| Total Hip | ||||||||||
| g/cm2 | - | - | 0.828 | 0.834 | 0.939 | 0.965 | 1.028 | 1.004 | 1.000 | 0.985 |
| BMC (g) | - | - | 22.6 | 21.8 | 25.6 | 26.8 | 28.2 | 27.8 | 27.6 | 27.4 |
| Area (cm2) | - | - | 27.3 | 26.1 | 27.3 | 27.7 | 27.4 | 27.7 | 27.6 | 27.8 |
| Z-score | - | - | −1.1 | −1.0 | −0.1 | +0.1 | +0.6 | +0.5 | +0.4 | +0.3 |
*
BMD studies were performed first using a dual photon absorptiometer (DP3 analyzer; Lunar) and then using DXA (Lunar Prodigy scanners) at the Hospital Clinic Barcelona.