Table 4.
Association of asthma medications with the risk of MI among active asthmatic patients
Medication | MI (n=46) | No MI (n=19) | Odds ratios (95%CI) | P-values* |
---|---|---|---|---|
Any treatment: | ||||
Yes | 34 (65%) | 18 (35%) | 0.16 (0.02, 1.31) | p=0.09 |
No | 12 (92%) | 1 (8%) | 1.0 (referent) | |
ICS treatment: | ||||
Yes | 22 (65%) | 12 (35%) | 0.53 (0.18, 1.60) | p=0.26 |
No | 24 (77%) | 7 (23%) | 1.0 (referent) | |
SCS treatment: | ||||
Yes | 2 (100%) | 0 (0%) | -** | -** |
No | 44 (70%) | 19 (30%) | ||
SABA treatment: | ||||
Yes | 29 (66%) | 15 (34%) | 0.45 (0.13, 1.60) | p=0.22 |
No | 17 (81%) | 4 (19%) | 1.0 (referent) | |
LABA treatment: | ||||
Yes | 12 (67%) | 6 (33%) | 0.76 (0.24, 2.46) | p=0.65 |
No | 34 (72%) | 13 (28%) | 1.0 (referent) |
p-values for comparison of active asthmatics with and without use of asthma medications (within 3 months prior to the index date of MI) derived from univariate (unmatched) logistic regression modeling;
model estimates for testing the association between SCS treatment and MI risk were not presented due to small number of subjects with SCS treatment. MI: myocardial infarction; ICS: inhaled corticosteroid; SCS: systematic corticosteroid; SABA: short acting beta agonist; LABA: long acting beta agonist