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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Semin Immunopathol. 2016 May 25;38(5):581–603. doi: 10.1007/s00281-016-0565-1

Fig 2.

Fig 2

FcεRIα and FcεRIα-bearing cells can contribute to acquired resistance to RVV. A, Outline of experiments with Fcer1a−/− and control (Fcer1a+/+) C57BL/6 mice (panels B-E). B and C, Serum RVV-specific IgG1 (B) and total IgE (C) levels. D and E, Body temperature (D) and survival (E). F, Outline of serum transfer experiments involving MC-deficient C57BL/6 mice (G and H). G and H, Body temperature (G) and survival (H). Data were pooled from 3 experiments (n=9-17/group). In B and C, data are shown as individual values and mean±SEM. P values were determined as follows: Mann-Whitney test (B and C); Student t test (D and G); Mantel-Cox test (E and H). *P<0.05, ** P<0.01, and *** P<0.001. n.d., Not detectable. This is a reproduction of Fig. 4 from Starkl P, Marichal T, Gaudenzio N, Reber LL, Sibilano R, Tsai M, Galli SJ. IgE antibodies, FcεRIα and IgE-mediated local anaphylaxis can limit snake venom toxicity. J Allergy Clin Immunol, 2016; 137: 246-57 (ref. [148]), reprinted with the permission of the publisher, Elsevier.