Table 1.
SNPTEST results for exploratory population for the six highest associated SNPs.
| BiPN (grade ≥ 2) | No BiPN or grade 1 BiPN | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP | Chr. | Allele A | Allele B | #AA | #AB | #BB | #AA | #AB | #BB | ORAB/AA (95% CI) | ORBB/AA (95% CI) | ORglobal (95% CI) | Ptrend |
| rs10862339 | 12 | A | C | 40 | 79 | 36 | 147 | 135 | 32 | 2.15 (1.38-3.36) | 4.13 (2.29-7.46) | 2.05 (1.55-2.71) | 5.47 × 10−7 |
| rs1344016 | 12 | A | G | 41 | 79 | 35 | 145 | 135 | 34 | 2.07 (1.33-3.23) | 3.64 (2.03-6.54) | 1.94 (1.47-2.56) | 3.81 × 10−6 |
| rs2414277 | 15 | T | C | 21 | 70 | 64 | 86 | 155 | 73 | 1.93 (1.25-3.03) | 3.57 (2.00-6.25) | 1.92 (1.45-2.56) | 6.17 × 10−6 |
| rs2839629 | 21 | G | A | 33 | 79 | 43 | 128 | 137 | 49 | 1.52 (0.93-2.50) | 3.45 (1.96-5.88) | 1.89 (1.45-2.50) | 7.64 × 10−6 |
| rs4776196 | 15 | T | C | 21 | 70 | 64 | 85 | 155 | 74 | 1.92 (1.23-2.94) | 3.45 (1.96-6.25) | 1.89 (1.43-2.50) | 9.31 × 10−6 |
| rs11145770 | 9 | G | A | 46 | 72 | 37 | 141 | 144 | 29 | 2.56 (1.45-4.55) | 3.85 (2.17-7.14) | 1.89 (1.43-2.50) | 9.70 × 10−6 |