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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: J Urol. 2016 Mar 2;196(3):721–726. doi: 10.1016/j.juro.2016.02.2963

Table 3.

Total number of tests received during 5 years of follow-up for prostate cancer patients on active surveillance

Total tests received during 5 years of active surveillance # (%) of all men
n=1349
# (%) of low risk
n=258
Median PSA tests (IQR) 11 (8) 10 (5)
≥5 PSA tests (every year) 1222 (90.6%) 242 (93.8%)
≥10 PSA tests (every 6 mos for 5 years) 798 (59.2%) 152 (58.9%)
≥20 PSA tests (every 3 mos for 5 years) 138 (10.2%) 18 (7.0%)
Median MRI (IQR) 0 (0) 0 (0)
≥1 MRI 167 (12.4%) 31 (12.0%)
≥2 MRI 48 (4.7%) 31 (12.0%)
≥3 MRI 48 (4.7%) 11 (4.3%)
Median biopsies after diagnosis* 1 (1) 1 (1)
≥2 biopsies after diagnosis* 458 (34.0%) 119 (46.1%)
≥3 biopsies after diagnosis* 196 (14.5%) 53 (20.5%)
≥4 biopsies after diagnosis* 89 (6.6%) 27 (10.5%)
Combo: ≥10 PSA tests and ≥2 biopsies 296 (21.9%) 83 (32.2%)
Combo (Prostate Cancer Research International Active Surveillance study 8): ≥14 PSA and ≥2 biopsies 150 (11.1%) 34 (13.2%)
Combo (Hopkins14): ≥10 PSA tests and ≥4 biopsies 68 (5.0%) 23 (8.9%)
*

All men were required to have one biopsy within 2 years after diagnosis for inclusion in the study, so 2 biopsies means 1 additional biopsy beyond the necessary biopsy for inclusion to the cohort. These categories are not mutually exclusive (i.e. men who had ≥4 biopsies after diagnosis are also counted as having ≥3 and ≥2 biopsies.