Table 1.
Demographic Characteristics of Women in PPCOS II by Quartile of Baseline AMH Level
| Characteristicsa | AMH (ng/mL)b |
|||||
|---|---|---|---|---|---|---|
| Overall | Quartile1: <3.58 | Quartile 2: 3.58–6.19 | Quartile 3: 6.20–10.23 | Quartile 4: >10.23 | P-valuec | |
| n, (%) | 748 | 187 (25) | 187 (25) | 187 (25) | 187 (25) | |
| Age, y | 28.9 ± 4.2 | 30.1 ± 4.6 | 28.2 ± 3.9 | 28.7 ± 4.1 | 28.5 ± 4.2 | <.0001 |
| BMI, kg/m2 | 35.1 ± 9.2 | 39.7 ± 9.7 | 35.0 ± 8.6 | 34.5 ± 8.2 | 31.2 ± 8.3 | <.0001 |
| Waist circumference, cm | 105.9 ± 20.5 | 114.7 ± 19.6 | 105.8 ± 19.0 | 105.3 ± 19.5 | 97.7 ± 20.3 | <.0001 |
| Hirsutism, mFG score | ||||||
| Mean ± sd | 17.0 ± 8.5 | 17.2 ± 8.5 | 17.5 ± 8.4 | 17.3 ± 8.8 | 15.9 ± 8.4 | .27 |
| mFG <8 | 97 (13) | 17 (9) | 22 (12) | 28 (15) | 30 (16) | .12 |
| mFG 8–16 | 276 (37) | 80 (43) | 60 (32) | 64 (34) | 72 (39) | |
| mFG >16 | 375 (50) | 90 (48) | 105 (56) | 95 (51) | 85 (45) | |
| Insulin, μIU/mL | 19.3 ± 27.0 | 24.8 ± 42.6 | 18.6 ± 17.2 | 18.9 ± 21.8 | 14.7 ± 17.4 | <.0001 |
| Glucose, mg/dL | 86.0 ± 12.6 | 89.3 ± 15.2 | 86.0 ± 10.8 | 84.7 ± 12.0 | 84.2 ± 11.5 | .0003 |
| HOMA-IR | 4.4 ± 9.1 | 6.1 ± 16.2 | 4.0 ± 3.6 | 4.2 ± 6.1 | 3.2 ± 4.2 | <.0001 |
| T, ng/dL | 55.0 ± 28.8 | 40.3 ± 19.3 | 53.5 ± 31.0 | 57.6 ± 25.3 | 68.7 ± 30.7 | <.0001 |
| LH, mIU/mL | 11.1 ± 8.5 | 8.6 ± 8.0 | 11.7 ± 8.8 | 11.3 ± 7.2 | 13.0 ± 9.4 | <.0001 |
| Current smokingd | 111 (35) | 25 (34) | 31 (33) | 28 (39) | 27 (34) | .88 |
| Treatment | ||||||
| Clomiphene Citrate | 375 (50) | 91 (49) | 90 (48) | 99 (53) | 95 (51) | .78 |
| Letrozole | 373 (50) | 96 (51) | 97 (52) | 88 (47) | 92 (49) | |
Abbreviation: ; mFG, modified Ferriman-Gallwey.
a
Values are Mean ± sd and n (%) as indicated.
b
AMH levels not available for two participants (one in each treatment group of the original trial).
c
Two-sided P-values for continuous variables calculated using ANOVA or the Kruskal-Wallis test, and for categorical variables using χ2 tests or Fisher's exact test where appropriate.
d
There were 430 values missing for current smoking status.