. 2016 May 26;101(9):3288–3296. doi: 10.1210/jc.2016-1340

Table 2.

AMH, AMH per Follicle, and Antral Follicle Count by Ovulation Induction Dose at First Ovulatory Response Overall and by Treatment Group Unadjusted and Adjusted For Age, BMI, T, and Insulin

Dose at First Ovulatory Response¹	Unadjusted			Adjusted
Dose at First Ovulatory Response¹	Overall²	Clomiphene	Letrozole	Overall	Clomiphene	Letrozole
AMH
First dose	4.90 (4.38, 5.47)^a	5.45 (4.66, 6.38)^a	4.43 (3.79, 5.18)^a	4.75 (4.31, 5.23)^a	4.94 (4.29, 5.70)^a	4.66 (4.08, 5.33)^a
Second dose	6.07 (5.39, 6.83)^ab	5.43 (4.53, 6.52)^a	6.56 (5.60, 7.68)^b	5.98 (5.40, 6.63)^b	5.74 (4.89, 6.74)^ab	6.05 (5.28, 6.93)^b
Third dose	6.04 (5.34, 6.84)^ab	6.17 (5.19, 7.34)^a	5.92 (4.96, 7.07)^ab	6.21 (5.58, 6.92)^b	6.41 (5.50, 7.48)^ab	5.97 (5.13, 6.95)^ab
Never ovulated	6.87 (5.99, 7.88)^b	6.81 (5.77, 8.04)^a	6.97 (5.49, 8.85)^b	7.09 (6.29, 7.99)^b	7.01 (6.04, 8.13)^b	7.33 (5.96, 9.01)^b
P-trend	0.0002	0.04	0.002	<0.0001	0.0006	0.0004
AMH per follicle
First dose	0.12 (0.10, 0.14)^ac	0.13 (0.11, 0.17)^a	0.11 (0.09, 0.13)^a	0.12 (0.10, 0.13)^a	0.12 (0.10, 0.14)^a	0.11 (0.09, 0.14)^a
Second dose	0.16 (0.14, 0.19)^b	0.14 (0.11, 0.18)^a	0.17 (0.14, 0.21)^b	0.16 (0.14, 0.18)^b	0.15 (0.12, 0.19)^ab	0.16 (0.13, 0.19)^b
Third dose	0.16 (0.14, 0.19)^c	0.15 (0.12, 0.19)^a	0.17 (0.14, 0.22)^b	0.17 (0.15, 0.20)^b	0.16 (0.13, 0.20)^ab	0.18 (0.14, 0.21)^b
Never ovulated	0.17 (0.14, 0.21)^bc	0.18 (0.14, 0.23)^a	0.15 (0.11, 0.21)^ab	0.18 (0.15, 0.21)^b	0.19 (0.15, 0.23)^a	0.16 (0.12, 0.21)^ab
P-trend	0.002	0.05	0.008	<0.0001	0.002	0.004
Antral Follicle Count
First dose	41.3 (38.2, 44.6)^a	40.9 (36.6, 45.7)^a	41.6 (37.5, 46.3)^ab	41.3 (38.3, 44.6)^a	41.7 (37.4, 46.6)^a	41.3 (37.1, 45.9)^ab
Second dose	38.4 (35.4, 41.7)^a	38.7 (34.1, 43.9)^a	38.2 (34.3, 42.5)^ab	38.4 (35.3, 41.6)^a	37.9 (33.4, 42.9)^a	38.5 (34.5, 42.9)^ab
Third dose	36.9 (33.9, 40.2)^a	40.0 (35.4, 45.1)^a	34.1 (30.3, 38.5)^a	36.8 (33.8, 40.1)^a	39.8 (35.3, 44.9)^a	34.2 (30.3, 38.7)^a
Never ovulated	40.6 (36.9, 44.6)^a	38.3 (34.1, 43.1)^a	45.2 (38.4, 53.3)^b	40.7 (36.9, 44.7)^a	38.2 (34.0, 43.0)^a	45.2 (38.3, 53.3)^b
P-trend	0.45	0.52	0.65	0.45	0.39	0.73

Dose: For letrozole: first dose, 2.5 mg; second dose, 5.0 mg; third dose, 7.5 mg; and for clomiphene: first dose, 50 mg; second dose, 100 mg; third dose, 150 mg.

Values are geometric means and 95% CIs. Labeled means without a common letter differ. P < .05 (adjusted for multiple comparisons).