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. 2016 Jul 6;101(9):3516–3525. doi: 10.1210/jc.2016-1334

Table 4.

qBEI Results

BMDD Controls* Proband 1 Proband 2 Proband 3 Proband 4 Proband 5 Proband 6 OI Type I** OI Type VII***
Cancellous bone n = 54 n = 19 n = 4
    CaMean [wt% Ca] 20.95 (0.57) 21.79 21.02 23.02 21.72 22.70 22.43 22.43 (0.63) 21.65 [21.48; 21.75]
    CaPeak [wt% Ca] 21.66 (0.52) 23.74 23.40 24.09 23.05 24.24 25.13 23.39 (0.57) 22.43 [22.30; 22.49]
    CaWidth [Δwt% Ca] 3.47 [3.12; 3.64] 2.95 4.33 2.78 3.64 3.15 4.33 3.08 (0.28) 3.21 [3.04; 3.29]
    CaLow [% bone area] 6.14 [4.90; 7.99] 11.89 15.09 8.16 9.66 10.19 12.79 5.94 (2.05) 6.04 [5.72; 6.46]
    CaHigh [% bone area] 0.89 [0.43; 1.47] 10.45 12.42 21.33 9.21 20.04 33.95 7.54 [5.00; 11.82] 2.52 [1.96; 3.20]
Cortical bone n = 53 n = 19 n = 4
    CaMean [wt% Ca] 20.45 [19.68; 21.04] 21.90 22.34 22.32 22.46 NA NA 22.51 (0.46) 21.72 [21.71; 21.87]
    CaPeak [wt% Ca] 21.14 [20.62; 21.75] 23.57 23.74 23.22 23.57 NA NA 23.29 (0.48) 22.75 [22.40; 23.11]
    CaWidth [Δwt% Ca] 3.81 [3.38; 4.38] 3.29 3.47 3.29 3.30 NA NA 3.28 (0.25) 4.10 [3.64; 4.57]
    CaLow [% bone area] 9.06 [6.22; 15.00] 9.95 8.20 6.72 6.78 NA NA 4.60 (0.80) 6.01 [5.41; 7.87]
    CaHigh [% bone area] 0.46 [0.28; 1.22] 10.84 13.62 10.32 12.13 NA NA 8.60 (4.00) 8.11 [4.83; 11.14]

Abbreviation: NA, not available. Reference data are shown as mean (SD) or median [25%; 75%] for healthy children* (28), children with OI type I** (29), and patients with OI type VII*** (30). BMDD values for cortical bone in children with OI type I were not published previously.