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. 2016 Jun 23;101(9):3345–3352. doi: 10.1210/jc.2016-1781

Figure 1.

Figure 1.

The tissue RARRES2 gene expression level is down-regulated in ACC but is not associated with patient prognosis. A, TaqMan real-time quantitative PCR reveals down-regulation of the RARRES2 gene expression level in our cohort of ACC samples as compared with benign adrenocortical tumors. Human RARRES2 expression is presented as % gene expression (= 2 −Δ(Ct RARRES2 − Ct GAPDH) × 100). B, RARRES2 expression as analyzed in NCBI-GEO database GSE10927. Data are presented as relative ratio to normal tissue. C, RARRES2 expression as analyzed in European Bioinformatics Institute database E-TABM-311. Data are presented as relative ratio to normal tissue. The tumor RARRES2 gene expression level is not associated with prognosis in 4 independent datasets, including our current cohort (D), patient cohort reported in GSE10927 (E), patient cohort reported in E-TABM-311 (F), and patient cohort reported in Demeure et al (26) (G). High and low RARRES2 groups were defined by median tissue gene expression. ns, not significant.