Table 2.

EVs in non-pregnant women with preeclampsia-associated risk factors compared to non-pregnant women without preeclampsia-associated risk factors

Risk factor	Extracellular vesicles	Results	Reference
Obesity	Endothelial-derived	↑	Stephanian et al. [17]
	Platelet-derived	↑	Stephanian et al. [17]
Diabetes mellitus	Endothelium-derived	↑	Sabatier et al. [18]
		↑	Tramontano et al. [19]
	Leukocyte-derived	No difference	Zhang et al. [20]
	Platelet-derived	↑	Zhang et al. [20]
		↑	Strano et al. [21]
Hypertension	Endothelium-derived	↑	Preston et al. [22]
	Platelet-derived	↑	Preston et al. [22]
Systemic lupus erythematosus	Leukocyte-derived	↑	Lacroix et al. [27]
		↓	Neilson et al. [24]
	Endothelium-derived	↑	Lacroix et al. [27]
		No difference	Neilson et al. [24]
	Platelet-derived	↑	Stephanian et al. [17]
Antiphospholipid syndrome	Endothelium-derived	↑	Dignat-George et al. [25]
	Leukocyte-derived	↑	Dignat-George et al. [25]
Sickle cell anemia	Platelet-derived	↑	Wun et al. [26]