Table 1.
Saline-treated (n = 15) | Carrageenan-treated (n = 38) | % Change vs saline-treated | |
---|---|---|---|
Depth (μm) | 677 ± 31 | 747 ± 21 | NA |
Threshold (mA) | |||
Aβ | 0.14 ± 0.01 | 0.19 ± 0.01## | 130 |
C | 1.47 ± 0.08 | 1.81 ± 0.10* | 124 |
Latency (ms) | |||
Aβ | 7.6 ± 0.79 | 7.3 ± 0.40 | 96 |
C | 182.3 ± 8.76 | 191.0 ± 8.50 | 105 |
Electrically evoked responses (number of APs) | |||
Aβa | 121 ± 10 | 126 ± 8 | 104 |
Aβb | 143 ± 10 | 145 ± 8 | 101 |
Aδb | 91 ± 16 | 148 ± 17## | 163 |
Cb | 431 ± 49 | 497 ± 41 | 114 |
PDb | 352 ± 49 | 381 ± 37 | 106 |
Inputb | 271 ± 51 | 368 ± 60 | 136 |
WUb | 505 ± 60 | 502 ± 46 | 100 |
Characteristics of spinal WDR neurones recorded at approximately 30 h following intraplantar injection of 2 % λ-carrageenan or saline
*p < 0.05 unpaired t test, ## p < 0.01 Mann-Whitney U test
APs action potentials, NA not applicable
aResponses electrically evoked by 3× Aβ-fibre threshold
bResponses electrically evoked by 3× C-fibre threshold