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. 2016 Sep 2;13(1):233. doi: 10.1186/s12974-016-0676-6

Table 1.

Comparison of characteristics of WDR neurones in carrageenan versus saline-treated rats

Saline-treated (n = 15) Carrageenan-treated (n = 38) % Change vs saline-treated
Depth (μm) 677 ± 31 747 ± 21 NA
Threshold (mA)
 Aβ 0.14 ± 0.01 0.19 ± 0.01## 130
 C 1.47 ± 0.08 1.81 ± 0.10* 124
Latency (ms)
 Aβ 7.6 ± 0.79 7.3 ± 0.40 96
 C 182.3 ± 8.76 191.0 ± 8.50 105
Electrically evoked responses (number of APs)
 Aβa 121 ± 10 126 ± 8 104
 Aβb 143 ± 10 145 ± 8 101
 Aδb 91 ± 16 148 ± 17## 163
 Cb 431 ± 49 497 ± 41 114
 PDb 352 ± 49 381 ± 37 106
 Inputb 271 ± 51 368 ± 60 136
 WUb 505 ± 60 502 ± 46 100

Characteristics of spinal WDR neurones recorded at approximately 30 h following intraplantar injection of 2 % λ-carrageenan or saline

*p < 0.05 unpaired t test, ## p < 0.01 Mann-Whitney U test

APs action potentials, NA not applicable

aResponses electrically evoked by 3× Aβ-fibre threshold

bResponses electrically evoked by 3× C-fibre threshold