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. 2016 Sep 2;13(1):233. doi: 10.1186/s12974-016-0676-6

Table 4.

Effects of spinal AT-RvD1 versus morphine on evoked responses of spinal neurones in MIA- and saline-treated rats

Saline-treated (n = 7) MIA-treated (n = 9)
AT-RvD1 Morphine 1 μg AT-RvD1 Morphine 1 μg
15 ng 150 ng 15 ng 150 ng
5 ± 7 6 ± 5 28 ± 6 1 ± 8 1 ± 9 2 ± 7#
−5 ± 10 −10 ± 13 47 ± 7 11 ± 8 14 ± 10 40 ± 6
C −4 ± 7 −13 ± 9 60 ± 14 10 ± 7 3 ± 8 35 ± 8
PD −6 ± 14 −16 ± 15 70 ± 12 16 ± 24 9 ± 14 55 ± 9
Input −5 ± 15 −19 ± 21 71 ± 12 −2 ± 12 2 ± 14 58 ± 11
WU −12 ± 13 −20 ± 16 62 ± 13 17 ± 19 12 ± 12 34 ± 6

Comparison of group effects of AT-RvD1 (15, 150 ng/50 μl) and morphine (1 μg/50 μl) on electrically evoked responses of spinal WDR neurones in MIA-treated rats versus saline-treated rats, expressed as % maximal inhibition. Note that negative values indicate facilitation

# p < 0.05 Mann-Whitney U test versus saline-treated rats