Table 2.
Results of immunohistochemistry and description of MMP-14/CD44 co-expression group
| Early-stage (n = 23) | Advanced-stage (n = 74) | p value* | |
|---|---|---|---|
| MMP-14 Overall Score (number of patients) | 0.07 | ||
| 0 | 8 | 11 | |
| 1 | 10 | 42 | |
| MMP-14 stroma (number of patients) | 0.03 | ||
| no | 4 | 25 | |
| weak | 14 | 23 | |
| strong | 0 | 5 | |
| CD 44 Overall Score | 0 | ||
| 0 | 6 | 47 | |
| 1 | 15 | 21 | |
| E-cadherin Overall Score | n.s. | ||
| 0 | 0 | 1 | |
| 1 | 21 | 67 | |
| Vimentin epithelial score | 30 % | 32 % | n.s. |
| Group with co-expression MMP-14-CD44a | 5 | 14 | |
| Histological subtype | |||
| Serous | 1 | 9 | |
| Mucinous | 1 | 1 | |
| Endometroid | 1 | 0 | |
| Clear cell | 2 | 1 | |
| Adenocarcinoma unspecified | 0 | 2 | |
| Mixed | 0 | 1 | |
| Grade | |||
| Low-grade | 1 | 3 | |
| High-grade | 4 | 11 | |
| Debulking | |||
| Complete | 11 | ||
| Incomplete | 3 | ||
| E-cadherin Overall Score | |||
| 0 | 0 | 1 | |
| 1 | 5 | 13 | |
| Vimentin epithelial score | 36 % | 34 % | |
*p value based on T-test and chi-square between early-stage and advanced-stage when appropriate
anumbers too small for statistical analysis, n.s. not significant