Table 3.
Pulse wave velocity (m/s) at age 9 years in relation to ANRIL DNA methylation
| CpG | Hg19 coordinates | β value | p value | Adjusted p |
|---|---|---|---|---|
| 1 | chr9: 21993721 | 0.0089 | 0.803 | 0.770 |
| 2 | chr9: 21993697 | 0.0173 | 0.622 | 0.592 |
| 3 | chr9: 21993694 | −0.053 | 0.357 | 0.723 |
| 4 | chr9: 21993654 | 0.0016 | 0.967 | 0.621 |
| 5 | chr9: 21993645 | 0.0663 | 0.037 | 0.026 |
| 6 | chr9: 21993638 | 0.0207 | 0.583 | 0.345 |
| 7 | chr9: 21993629 | 0.0154 | 0.736 | 0.659 |
| 8 | chr9: 21993603 | 0.0258 | 0.531 | 0.322 |
| 9 | chr9: 21993583 | 0.0828 | 0.176 | 0.087 |
β values represent a 10 % change in methylation. DNA methylation levels were determined via pyrosequencing. Linear regressions were used to compare methylation and pulse wave velocity. Adjusted p values are adjusted for age, sex, total fat mass at 8 years and mother smoking during pregnancy