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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Hepatology. 2016 Apr 15;64(4):1343–1355. doi: 10.1002/hep.28530

Figure 2. Pathogenesis and molecular mechanisms that trigger liver failure, SIRS, and multi-organ failure in AH.

Figure 2

Excessive drinking in alcoholics with underlying ALD induces hepatocellular damage, induces systemic inflammation, and impairs liver regeneration, resulting in liver failure and other complications in AH.