Effects of trichostatin A (TSA) on anxiety-like behaviors of adolescent intermittent ethanol (AIE) - and normal saline (AIS)-exposed adult rats, as measured by the light dark box (LDB) exploration test. The general activity measured as total ambulation was not different among the treatment groups. Values are represented as the mean (±SEM) of 10 rats per group. *Significantly different from respective control groups [p<0.001, two-way ANOVA (AIE effect, F1, 36= 8.7, p<0.01; TSA effect, F1, 36= 9.4, p<0.01; AIE × TSA interaction, F1, 36= 28.5, p<0.001) followed by Tukey’s test].