Table 2.
IVF cycle characteristics, endocrine parameters, and outcomes in women receiving GnRHa alone versus dual trigger
| GnRHa trigger (n = 108) |
Dual trigger (n = 66) |
|
|---|---|---|
| Starting dose of gonadotropins (IU)* | 150 (125–225) | 225 (150–300) |
| Total dose of gonadotropins (IU) | 2325 (1812–2931) | 2512 (1800–3675) |
| Days of stimulation* | 11 (9–12) | 11 (10–12) |
| Maximum E2 (pg/mL)* | 4360 (3517–5704) | 3541 (2943–5014) |
| Follicles >15 mm day−1 of trigger | 13 (10–16) | 14 (12–16) |
| Total follicles day of trigger* | 31 (25–35) | 28 (22–34) |
| E2 levels on day of trigger (pg/mL) | 3604 (2843–4536) | 2993 (2597–4280) |
| LH levels on day of trigger (mIU/mL) | 0.6 (0.3–1.4) | 0.7 (0.3–1.4) |
| E2 levels post-trigger (pg/mL) | 4329 (2295–5704) | 3541 (2662–4913) |
| LH levels post-trigger (mIU/mL)* | 52.2 (36–76) | 56.5 (39–85) |
| P4 levels post-trigger (ng/mL)a | 6.0 (4.5–9.0) | 6.7 (5.1–9.5) |
| Total number oocytes retrieved | 16.5 (11–21.5) | 17.5 (12–24) |
| Oocyte maturity (%)** | 70 (56–85) | 82 (74–91) |
| No oocytes retrieved (%) | 3 (2.8) | 0 |
| OHSS (%)** | 0 | 6 (9) |
| Severe OHSS (%)** | 0 | 4 (6) |
Data are median (interquartile range)
*p < 0.05; **p < 0.01
aFive individuals in the GnRHa trigger group did not have post-retrieval progesterone values available for analysis