Table 1.

Clinical and demographic characteristics of 419 APC mutation carriers

	<100 adenomas (N = 231)	≥100 adenomas (N = 188)
Gender
Male (%)	111 (48 %)	99 (53 %)
Polyposis
Mean age at diagnosis, years	26.5	27.6
Mode of diagnosis
Symptomatic (%)	34 (15 %)	72 (38 %)
Screening (%)	197 (85 %)	116 (62 %)
CRC (%)	19 (8 %)	30 (16 %)
Mean age at CRC, years (range)	43.4	40.4
Mutation group
Attenuated (%)	50 (22 %)	20 (11 %)
Intermediate (%)	172 (74 %)	141 (75 %)
Severe (%)	9 (4 %)	27 (14 %)
Last follow-up
Age, years	34.7	40.4
Status at last follow-up
Alive (%)	221 (96 %)	165 (88 %)
Dead due to CRC (%)	9 (4 %)	14 (7 %)
Dead due to other cause (%)	1 (0.4 %)	9 (5 %)