Table 2.
Test for Hardy–Weinberg equilibrium
| SNP | Chromosome region | Alleles major/minor | Risk allele | HWE P value | MAFa (allele) | Gene | Reference |
|---|---|---|---|---|---|---|---|
| rs6691170 | 1q41 | G/T | T | 0.2182 | 0.321 (T) | DUSP10 | [9] |
| rs6687758 | 1q41 | A/G | G | 0.1461 | 0.160 (G) | DUSP10 | [9] |
| rs10936599 | 3q26.2 | C/T | C | 0.8902 | 0.229 (T) | MYNN | [9] |
| rs16892766 | 8q23.3 | A/C | C | 0.5592 | 0.091 (C) | EIF3H | [4] |
| rs6983267 | 8q24.21 | G/T | G | 0.2798 | 0.461 (T) | MYC | [5] |
| rs10795668 | 10p14 | G/A | G | 0.1723 | 0.311 (A) | Unknown | |
| rs3802842 | 11q23.1 | A/C | C | 0.6216 | 0.265 (C) | POU2AF1 | [6] |
| rs7136702 | 12q13.13 | C/T | T | 0.8298 | 0.346 (T) | LARP4 | [9] |
| rs11169552 | 12q13.13 | C/T | C | 0.6966 | 0.247 (T) | DIP2B | [9] |
| rs4444235 | 14q22.2 | T/C | C | 0.2362 | 0.432 (C) | BMP4 | [7] |
| rs4779584 | 15q13.3 | C/T | T | 1 | 0.159 (T) | GREM1 | [8] |
| rs9929218 | 16q22.1 | G/A | G | 0.4207 | 0.304 (A) | CDH1 | [7] |
| rs4939827 | 18q21.1 | C/T | T | 0.04911 | 0.435 (T) | SMAD7 | [10] |
| rs10411210 | 19q13.11 | C/T | C | 0.07355 | 0.127 (T) | RHPN2 | [7] |
| rs961253 | 20p12.3 | C/A | A | 0.1397 | 0.311 (A) | BMP2 | [7] |
| rs4925386 | 20q13.33 | C/T | C | 0.4955 | 0.311 (T) | LAMA5 | [9] |
aMinor allele frequency (MAF) in patients included in this study