Table 3.
Frequency and percentage of microsatellite alterations (LOH and MSI) in 50 ESCC tumor
| Marker | Related Gene(s) | LOH+ (%) | MSI+ (%) | Total (%) |
|---|---|---|---|---|
| D2S123 | hMSH2 | 0 (0) | 4 (8) | 8 |
| D5S2501 | APC | 3 (6) | 10 (20) | 26 |
| D13S260 | BRCA2 | 13 (26) | 5 (10) | 10 |
| D13S267 | BRCA2 | 9 (18) | 5 (10) | 28 |
| D9S171 | p14, p15, p16 | 1 (2) | 9 (18) | 20 |
| TP53 | P53 | 6 (12) | 9 (18) | 30 |
| Total | 33 *(66) | 20 *(40) | - |
*
Some samples had more than one LOH+ and/or instable marker, therefore the total number is less than the addition of values for each marker (LOH: loss of heterozygosity, MSI: microsatellite instability)