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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Surg Oncol Clin N Am. 2016 Jul 30;25(4):761–773. doi: 10.1016/j.soc.2016.05.007

Table 1.

Genomic alterations in liposarcoma

Histologic subtypes Genomic
alterations		 Affected oncogenes Clinical correlation
Well- and dedifferentiated 12q13-15 amplification MDM2 and CDK4 N/A
3p14-21 loss Unknown Dedifferentiation
11q23-24 loss Unknown Dedifferentiation, genomic
instability
19q13 loss Unknown Dedifferentiation, poor
prognosis
Myxoid/round cell FUS-DDIT3 translocation Unknown N/A
Pleomorphic Rb/p53 loss Rb and p53 N/A