Table 2. Demography of the Patientsa.
Group | HD | AC | ACH | Cir | HCC |
---|---|---|---|---|---|
Age (y) Means (minimal - maximal) | 37 (27 - 55) | 31 (23 - 51) | 40 (20 - 50) | 41 (28 - 56) | 49 (37 - 67) |
F/M | 1/5 | 1/5 | 0/6 | 0/6 | 1/5 |
HBsAg (0 - 1.0 S/CO) | Neg | 200.74 ± 141.17 | 75.14 ± 76.12 | 98.50 ± 44.08 | 112.01 ± 60.35 |
HBeAg (0 - 0.28 PEIU/ml) | Neg | 1433 ± 1483.40 | 186.88 ± 218.20 | 76.88 ± 152.49 | 11.99 ± 16.66 |
HBV-DNA < 2.70 copies/ml (log) | Neg | 7.88 ± 1.32 | 5.00 ± 20.4 | 5.34 ± 1.07 | 5.81±1.25 |
TB (5.1 - 19 µmol/L) | Nor | 16.47 ± 3.73 | 107.80 ± 88.93 | 56.97 ± 29.05 | 17.77 ± 7.98 |
DB (1.7 - 6.8 µmol/L) | Nor | 6.15 ± 1.11 | 44.25 ± 37.81 | 24.35 ± 15.38 | 6.97 ± 1.97 |
ALT (5 - 40 u/L) | Nor | 32.53 ± 5.93 | 793.03 ± 1452.55 | 86.32 ± 59.52 | 55.78 ± 24.66 |
Necroinflammation score(N 0 - 18) | 0.5 ± 0.55 | 0.67 ± 0.47 | 14.83 ± 2.85 | 7.67 ± 1.25 | 3.5 ± 1.12 |
Fibrosis score (F 0 - 6) | 0 | 0 | 1.5 ± 0.5 | 6 ± 0 | 1.17 ± 0.68 |
aThe lesions of necroinflammation and fibrosis were graded according to the Ishak Modified HAI. The maximum possible scores for necroinflammation and fibrosis were 18 and 6, respectively.