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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Mol Cancer Ther. 2016 Jun 15;15(9):2055–2065. doi: 10.1158/1535-7163.MCT-15-1023

Figure 5. Cytotoxicity of acridine derivatives on human MM cell lines.

Figure 5

A. XTT cell viability assay of RPMI 8226 and MM1.R human MM cells treated with 0-6 μM of Compound 4, 5, 10 and 11 for 24 hours. Background-subtracted optical absorbance values normalized to vehicle treatment (set to 100%) ± SD were plotted over the indicated compound doses. B. Western blot analysis of a panel of UPR marker proteins for both types of cells that were treated with 0-3 μM Compound 4, 5, 10 and Compound 11 for 14 hours. β-actin was used as a loading control.