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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Exp Neurol. 2016 Apr 13;283(Pt B):560–572. doi: 10.1016/j.expneurol.2016.04.009

Table 2.

All Studies Using CNS-Derived Myelinating Cells That Met the Latter Inclusion Criteria.

Cell type: OPCs NRPs adult NSPCs embryonic
NSPCs
embryonic
GRPs
ESCs iPS-NSCs
Study: Bambakidis et al., 2004

Sun et al., 2014

Cao et al., 2010
Setoguchi et al., 2004 Hawryluk et al., 2014

Hofstetter et al., 2005

Karimi-Abdolrezaee et al., 2010

Mothe et al., 2013
Hu et al., 2012

Lu et al., 2010

Yasuda et al., 2011
Cao et al., 2005

Hu et al., 2013
McDonald et al.,1999 Salewski et al., 2015
Genetic /
Drug
Treatment:
Shh

TROY
inhibition

CNTF
Noggin minocycline+
cyclosporine,

Neurogenin-2,

ChABC,

HAMC-
rPDGF
Olig2/MBP
activated T
cells,

cyclosporin A,

No treatment
D15A,

Schwann
cell co-
transplant
No
treatment
No
treatment

Studies that met inclusion criteria were grouped into 7 broad categories of cell types used for transplantation. Relevant genetic or pharmacologic additions are identified within each study.

Abbreviations: ChABC=Chondroitinase ABC, CNTF=Ciliary Neurotrophic Factor, ESC=Embryonic Stem Cells, GRP=Glial Restricted Precursor Cells, HAMC-rPDGF=Hyaluronan And Methyl Cellulose covalently modified with recombinant rat Platelet-Derived Growth Factor-A, iPS-NSC=induced Pluripotent Stem derived-Neural Stem Cells, NPC=Neural Precursor Cells, NRP=Neural Restricted Precursor cells, NSPC=Neural Stem Progenitor Cells, OPC=Oligodendrocyte Precursor Cells, Shh=Sonic hedgehog.