Skip to main content
. Author manuscript; available in PMC: 2017 Sep 15.
Published in final edited form as: J Immunol. 2016 Aug 17;197(6):2400–2408. doi: 10.4049/jimmunol.1600138

Figure 2. IL-17 and TNF synergistically upregulate pro-inflammatory gene expression in PCs.

Figure 2

Production of IL-6, IL-8, CXCL5, and CCL20 transcripts by HUVECs (A), HDMECs (B), and PCs (C) after stimulation with 20ng/mL of recombinant human IL-17 (circle), TNF (square), or IL-17+TNF (inverted triangle) for the indicated time. To determine the presence of synergistic interactions, transcript levels from IL-17+TNF conditions were compared to the sum of the transcript levels from IL-17 alone and TNF alone [n=3, t-test, SEM]. *p<0.05, **p<0.01, ****p <0.0001.