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. Author manuscript; available in PMC: 2017 Sep 15.
Published in final edited form as: J Immunol. 2016 Aug 15;197(6):2187–2194. doi: 10.4049/jimmunol.1600793

Figure 5. Stat pathway and caspase1 activation in the kidney of Mer-KO mice with nephritis.

Figure 5

Kidney samples were prepared in RIPA buffer. Analysis of phosphorylation status of Stat3 and expression levels of SOCS3 at day 3 (A) and day 14 (B), and caspase-1 activation (C) during the development of NTS-nephritis was done by Western immunoblotting. Densitometry analysis to quantify ratio of phosphorylated Stat3 to total Stat3 and SOCS3 proteins to β-actin, respectively, is shown at the bottom. Representative Western images are shown. Experiments were independently repeated at least 2 times. Values are expressed as median with interquartile range. Statistical test is the Mann-Whitney test. **p<0.01, *p<0.05.