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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Neurobiol Dis. 2016 Jun 28;95:1–11. doi: 10.1016/j.nbd.2016.06.014

Fig. 8. Depletion of Dnm1 isoforms lowers seizure threshold.

Fig. 8

ECT threshold for Dnm1a deletion (left) and Dnm1b deletion (right) animals crossed with Dnm1+/Ftfl mice. Male and female data are shown together after rank and n-quantile normalization. Genotypes below indicate the alleles expressed for Dnm1: Dnm1+/+, Dnm1+/Ftfl, Dnm1aΔ/Ftfl, Dnm1aΔ/aΔ, Dnm1bΔ/Ftfl or Dnm1bΔ/bΔ. Number of animals tested is shown below genotype in parentheses. The combined data show that the reduced ECTs of the compound heterozygous mice were statistically significant (Student’s |t|-test, ***p<0.0001; **p<0.001; *p<0.01).