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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Brain Behav Immun. 2016 May 17;57:293–303. doi: 10.1016/j.bbi.2016.05.008

Figure 6.

Figure 6

Depressive-like behavior was evaluated using the social avoidance test. Social withdrawal was exacerbated when an aggressor was introduced in the social target trial (Trial 2) in RSD mice treated with vehicle, with a decreased time spent in the interaction zone, and this was reversed with (A) imipramine treatment. Bars represent the mean ± SEM. Means with asterisk (*) are significantly different from each other (p<0.05). Trial 1: time without intruder; Trial 2= time with intruder; RSD=Repeated Social Defeat; (s)=seconds