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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Cell Tissue Res. 2016 Jun 2;365(3):483–493. doi: 10.1007/s00441-016-2424-8

Figure 1. Recent approaches to reducing scar formation.

Figure 1

Schematic showing novel scientific approaches for decreasing scar formation, including targeting pro-fibrotic cell populations based on surface molecule expression. Modulation of cellular mechanotransduction pathways are another means to reduce scar formation, both at the molecular level, or macroscopically with dressings designed to offload tension at cutaneous wound sites. ADAM12, a disintegrin and metalloprotease 12; DPP4, dipeptidyl peptidase-4; FAK, focal adhesion kinase.