. Author manuscript; available in PMC: 2017 Sep 1.

Published in final edited form as: Cancer Prev Res (Phila). 2016 Jun 23;9(9):750–757. doi: 10.1158/1940-6207.CAPR-16-0060

Table 1.

Effect of AA supplementation on Fads1 mouse colonic mucosa eicosanoid and cannabinoid profiles¹,²

	Wt (0% AA)	Het (0% AA)	Null (0% AA)	Null (0.6% AA)	Null (2% AA)
(ng/mg protein)
PGE₁	0.68±0.10^a	0.95±0.18^ab	1.19±0.13^b	1.37±0.23^b	1.15±0.19^ab
PGE₂	10.40±1.51^c	7.99±1.69^b	1.11±0.31^a	5.65±0.50^ab	8.39±1.13^b
6-keto-PGF_1α	1.45±0.24^c	1.15±0.19^bc	0.08±0.02^a	0.60±0.06^ab	1.01±0.26^b
13-PGE₂	0.75±0.23^b	0.53±0.10^ab	0.00±0.00^a	1.13±0.21^b	0.71±0.18^ab
13-HODE	0.62±0.30^ab	1.36±0.57^b	0.12±0.01^a	0.38±0.05^ab	3.16±0.49^c
12-HETE	1.13±0.16^b	1.02±0.28^ab	0.26±0.07^a	0.84±0.14^ab	2.67±0.93^c
TXB₂	0.49±0.06^c	0.31±0.10^b	0.02±0.01^a	0.31±0.05^b	N/A³
PGD₂	6.62±1.63^b	5.70±1.62^b	0.44±0.07^a	8.60±0.84^b	N/A
AEA	0.15±0.02^b	0.11±0.01^b	0.04±0.00^a	0.24±0.05^c	N/A
2-AG	12.83±2.19^b	10.26±2.02^b	2.29±0.37^a	8.65±1.39^b	N/A
13-PGE₁	0.10±0.03	0.08±0.00	N/A	0.10±0.03	0.06±0.03
15-HETE	1.09±0.34	0.78±0.13	N/A	0.77±0.05	1.20±0.31
5-HETE	0.22±0.07^a	0.18±0.06^ab	N/A	0.40±0.04^b	0.42±0.11^b

Abbreviations: PG, prostaglandin; HODE, hydroxyl octadecadienoic acid; HETE, hydroxyl eicosatetraenoic acid; TX, thromoboxane; AEA, arachidonoyl ethanolamine; AG, arachidonoyl glycerol; 13-PGE₂, 13,14-dihydro 15-keto-PGE₂; 13-PGE₁, 13,14-dihydro 15-keto-PGE₁.

Values not sharing the same letter are significantly different (p < 0.05), mean ± SE, n= 4–11.

N/A, not available.