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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Cancer Prev Res (Phila). 2016 Jun 23;9(9):750–757. doi: 10.1158/1940-6207.CAPR-16-0060

Table 2.

Effect of Fads1 deficiency on AOM-induced ACF development

Wt Null p-value
# aberrant crypt/ focus
1 17.27±0.31 14.38±2.10 0.385
2 10.46±1.43 7.25±0.80 0.096
3 4.27±0.97 1.88±0.35 0.060
4 1.18±0.23 0.25±0.16 0.007
5+ 0.64±0.24 0.13±0.13 0.114
Colon length (cm) 3.66±0.29 3.76±0.14 0.791
Total ACF#/colon 33.82±4.28 23.88±2.56 0.088
ACF#/cm colon 9.83±1.28 6.38±0.66 0.047
High Multiplicity1 ACF#/colon 6.09±1.00 2.25±0.56 0.008
% High Multiplicity2 18.14±1.84 9.21±1.71 0.003
1

High Multiplicity ACF: foci containing 3 or more aberrant crypts.

2

Percentage of High Multiplicity: number of high multiplicity ACF divided by total number of ACF.

*

Significantly different (P < 0.05). Data represent means ± SE, n=8–11.