Table 3.
Environmental tobacco smoke (ETS) and adjusted percent changes in anti-Müllerian hormone (AMH) levels, Sister Study
| Environmental Tobacco Smoke (ETS) | N | % | Age adjusted % change and 95%CI | Multivariable adjusted % change and 95% CI a,b | |
|---|---|---|---|---|---|
| Total years of ETS | |||||
| None | 164 | 18.3 | 0.0 (referent) | 0.0 (referent) | |
| 0–9 | 138 | 15.4 | 9.2 (−30.5, 71.6) | 13.0 (−28.6, 78.8) | |
| 10 to 19 | 285 | 31.7 | 1.8 (−30.6, 49.54) | 10.0 (−25.8, 63.0) | |
| 20+ | 311 | 34.6 | −12.1 (−39.9, 28.4) | −3.5 (−35.1, 43.5) | |
| Adult ETS | |||||
| No | 411 | 45.2 | 0.0 (referent) | 0.0 (referent) | |
| Yes | 498 | 54.8 | −26.4 (−43.3, −4.5) | −21.0 (−39.6, 3.4) | |
| Years of adult ETS | |||||
| None | 411 | 45.0 | 0.0 (referent) | 0.0 (referent) | |
| 0–9 | 269 | 29.6 | −16.1 (−38.1, 13.9) | −12.2 (−35.5, 19.6) | |
| 10+ | 229 | 25.1 | −37.1 (−54.4, −13.1) | −31.9 (−51.7, −3.9) | |
| Childhood ETS | |||||
| No | 264 | 29.3 | 0.0 (referent) | 0.0 (referent) | |
| Yes | 637 | 70.7 | 12.6 (−15.5, 50.0) | 10.5 (−17.6, 48.0) | |
| Years of childhood ETS | |||||
| None | 264 | 29.0 | 0.0 (referent) | 0.0 (referent) | |
| 0–9 | 115 | 12.8 | 39.0 (−10.3, 115.2) | 38.7 (−11.4, 117.0) | |
| 10 to 17 | 170 | 18.9 | 20.7 (−17.9, 77.5) | 19.3 (−19.5, 76.8) | |
| 18 | 352 | 39.1 | 1.5 (−26.2, 39.7) | −1.1 (−28.5, 36.8) | |
| Combined adult/child ETS | |||||
| low childhood, low adult | 422 | 46.2 | 0.0 (referent) | 0.0 (referent) | |
| high childhood, low adult | 220 | 24.1 | −2.4 (−29.4, 34.9) | −7.4 (−33.3, 28.6) | |
| low childhood, high adult | 139 | 15.2 | −31.5 (−53.2, 0.3) | −31.3 (−53.4, 1.3) | |
| high childhood, high adult | 132 | 14.5 | −41.0 (−60.0, −12.8) | −39.6 (−59.3, −10.3) | |
| Maternal smoking during pregnancy | |||||
| Definitely Not | 491 | 57.0 | 0.0 (referent) | 0.0 (referent) | |
| Unsure | 129 | 15.0 | 30.9 (−11.3, 93.0) | 34.6 (−9.1, 99.3) | |
| Definitely | 241 | 28.0 | −4.5 (−29.7, 29.8) | −7.4 (−32.2, 26.4) | |
| Paternal Smoking, 3 months prior to pregnancy | |||||
| Definitely Not | 258 | 30.0 | 0.0 (referent) | 0.0 (referent) | |
| Unsure | 140 | 16.3 | −4.0 (−36.5, 45.2) | −8.1 (−39.7, 39.9) | |
| Definitely | 461 | 53.7 | −20.5 (−41.5, 7.9) | −21.2 (−42.3, 7.5) | |
| Anyone in household smoke during pregnancy | |||||
| Definitely Not | 305 | 35.5 | 0.0 (referent) | 0.0 (referent) | |
| Unsure | 159 | 18.5 | −17.0 (−443.5, 21.8) | −22.6 (−47.7, 14.4) | |
| Definitely | 395 | 46.0 | −20.0 (−40.7, 7.9) | −23.3 (−43.3, 3.9) | |
a
Associations for total years of ETS, adult ETS, and years of adult ETS were adjusted for age, parity, breastfeeding history, race, education and annual household income.
b
Associations for childhood ETS, years of childhood ETS, maternal smoking during pregnancy, paternal smoking 3 months prior and anyone smoking in the household were adjusted for age, race, maternal education and childhood household income